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In the absence of conventional lymphatics, drainage of interstitial fluid and solutes from the brain parenchyma to cervical lymph nodes is along basement membranes in the walls of cerebral capillaries and tunica media of arteries. Perivascular pathways are also involved in the entry of CSF into the brain by the convective influx/glymphatic system. The(More)
Development of cerebral amyloid angiopathy (CAA) and Alzheimer's disease (AD) is associated with failure of elimination of amyloid-β (Aβ) from the brain along perivascular basement membranes that form the pathways for drainage of interstitial fluid and solutes from the brain. In transgenic APP mouse models of AD, the severity of cerebral amyloid angiopathy(More)
We examine the application of current research in sparse signal recovery to the problem of channel estimation. Specifically, using an orthogonal frequency division multiplexed (OFDM) transmission scheme with pilot symbol assisted modulation (PSAM), we consider the problem of identifying a frequency selective channel from a limited number Q out of a possible(More)
—In many communication systems the channel impulse response can be characterized with a parametric form, though the channel estimation is often performed using an equivalent discrete-time linear time-invariant system (usually modeled as a Moving Average (MA) system). When the number of parameters which describe the channel is less than the number of(More)
Recently, new progress has been made in using basis expansion models for system identification with compressed sensing. To aid the application of these methodologies, we introduce a metric, called localized coherence, for choosing input signals that result in better estimation performance. Its definition is motivated through the analysis of the normalized(More)
— We propose an approach that enables increased range and throughput in over-the-horizon (OTH) High Frequency (HF) communications using a novel physical layer node cooperation scheme. By exploiting multiple (and sufficiently spaced apart) low-powered man-portable radios in a collaborative fashion, it will be possible to obtain diversity gains similar to(More)
In this chapter we describe in detail the tissue processing techniques we employ for the study of cerebral tissue by transmission electron microscopy (TEM). In particular, we explain a technique that enables quantification of changes in cerebral basement membranes at the ultrastructural level. This is significant, as age related pathological conditions(More)
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