Matthew Schmidt

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Using a whole-cell binding procedure with long incubations at low temperature and subsequent acid stripping, we have characterized an atypical endothelin (ET) receptor in primary rat cortical astrocyte cultures. We found the following: (a) no competition for 125I-ET-1 binding by the ET(A) antagonists BQ-123 and LU 135252 or the ET(B) agonist IRL 1620; (b)(More)
The Human Computer Interaction community is beginning to wrestle with the challenges of effective interaction design for groups collaborating in 3 dimensional virtual worlds. Understanding of the requirements and design processes necessary to support these new technologies is still emerging. While the gaming community has developed heuristics for game(More)
This paper describes a preliminary study which attempted to apply learning analytics methods to usage data generated by students with autism spectrum disorders using iSocial, a collaborative, three-dimensional virtual learning environment. Drawing from similar methods in the area of learning and content management systems, the work presented in this paper(More)
curriculum ABSTRACT This paper presents a case study of developing and implementing methods to capture, code and comprehend reciprocal social interactions in a three-dimensional virtual learning environment (3D VLE). The environment, iSocial, is being developed to help youth with autism spectrum disorders (ASD) develop social competencies. The approach to(More)
Online learning in K-12 and higher education has been growing rapidly, and open source software has the potential to improve the quality of e-learning. This chapter describes how FOSS enables turning e-learning from a potentially restrictive and narrow framing of the education experience to an emergent and social experience. The chapter will identify(More)
Stereotactic radiosurgery has long been recognized as the optimal form of management for high-grade arteriovenous malformations not amenable to surgical resection. Radiosurgical plans have generally relied upon the integration of stereotactic magnetic resonance angiography (MRA), standard contrast-enhanced magnetic resonance imaging (MRI), or computed(More)