ALK1 (ACVRL1) is a member of the TGFβ receptor family and is expressed predominantly by arterial endothelial cells (EC). Mutations in ACVRL1 are responsible for hereditary hemorrhagic telangiectasia type 2 (HHT2), a disease manifesting as fragile vessels, capillary overgrowth, and numerous arterio-venous malformations. Arterial EC also express EphrinB2,… (More)
The preliminary findings of an investigation into the effects of anaesthesia on middle ear function have shown a transient worsening lasting about 6 days. It is suggested that results of hearing tests carried out within a week of general anaesthesia should be treated with caution.