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BACKGROUND This study investigated the relationship between objectively measured physical fitness variables derived by cardiopulmonary exercise testing (CPET) and in-hospital morbidity after rectal cancer surgery. METHODS Patients scheduled for rectal cancer surgery underwent preoperative CPET (reported blind to patient characteristics) with recording of… (More)
Abrupt interruption or cessation of selective serotonin reuptake inhibitor (SSRI) treatment may result in discontinuation or treatment interruption symptoms. Recent reports suggested these symptoms occur more frequently with shorter half-life SSRIs. Previous studies indicated a 5-8-day treatment interruption resulted in fewer discontinuation-emergent… (More)
The Mersey estuary is highly contaminated with xenobiotics compared to the nearby Dee estuary. Male flounder, a migratory flatfish caught in the Mersey frequently contains high blood concentrations of the oestrogen controlled, female protein vitellogenin, suggesting that Mersey flounder have been exposed to endocrine disrupting contaminants. Males caught… (More)
Cocaine abuse is a major public health problem worldwide and is increasingly common in Europe. Oral use of cocaine in two patients resulted in unusual white lesions on their anterior maxillary gingivae/vestibule. GDPs should be alert to this newly described lesion.
To investigate the safety and efficacy of 0.25% hyperbaric bupivacaine for spinal anaesthesia in Caesarean section, we studied 60 parturients allocated randomly to one of three groups. According to the patient's height, groups 1, 2 and 3 received 3.2-3.6 ml (8-9 mg), 3.6-4.0 ml (9-10 mg) and 4.0-4.4 ml (10-11 mg) of 0.25% bupivacaine in 5% glucose,… (More)
In a double-blind, randomized, placebo-controlled study, 41 patients received clonidine 3 micrograms kg-1 or placebo at induction of isoflurane and nitrous oxide in oxygen anaesthesia. Metoprolol was also given to achieve a systolic arterial pressure of 80 mm Hg. Requirements for metoprolol were significantly less in the clonidine group (P < 0.00035), with… (More)
From 1998 to 2001 a total of 200 Ommastrephes bartramii (27 paralarvae) and 170 Sthenoteuthis oualani-ensis (14 paralarvae) were sampled from the Central North Pacific. One group of non-paralarval O. bartramii (n = 30) was sampled from farther northwest in 1996. The d 15 N of mantle muscle of non-paralarval O. bartramii (x = 12.4%) was significantly greater… (More)
Sir,—The article of Kitching, Walpole and Blogg 1 investigating removal of the laryngeal mask in anaesthetized and awake children merits further discussion. At our hospital we routinely use the laryngeal mask airway (LMA) in the general paediatric population for various ear, nose and throat (ENT) procedures. 2 Our standard practice is in accordance with… (More)
We describe a new technique of intubation for use in difficult paediatric airway cases utilizing the laryngeal mask airway, a Cook Airway Exchange Catheter and a paediatric intubation fibrescope. This method has a number of potential advantages over previously described methods.