Author pages are created from data sourced from our academic publisher partnerships and public sources.
Predicting drug-drug interactions in drug discovery: where are we now and where are we going?
- Matthew J. Hutzler, D. Messing, L. Wienkers
- Medicine, Biology
- Current opinion in drug discovery & development
Pressure on drug discovery research teams to identify successful drug candidates earlier on in the drug discovery process has led to the development of a variety of ADME in vitro assays, intended to… Expand
This chapter contains a comprehensive summary about molybdenum-containing hydroxylases and what role these enzymes play in drug metabolism. The molybdenum-containing hydroxylases of interest to drug… Expand
Bioactivation II: Phase I (Non-P450)
While cytochrome P450 enzymes are generally the primary focus of drug metabolism scientists, there are many other enzymes that may contribute to the biotransformation of xenobiotics and are perhaps… Expand