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Pressure on drug discovery research teams to identify successful drug candidates earlier on in the drug discovery process has led to the development of a variety of ADME in vitro assays, intended to… (More)
This chapter contains a comprehensive summary about molybdenum-containing hydroxylases and what role these enzymes play in drug metabolism. The molybdenum-containing hydroxylases of interest to drug… (More)
While cytochrome P450 enzymes are generally the primary focus of drug metabolism scientists, there are many other enzymes that may contribute to the biotransformation of xenobiotics and are perhaps… (More)