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- Publications
- Influence
Nuclear Epidermal Growth Factor Receptor Is a Functional Molecular Target in Triple-Negative Breast Cancer
- T. Brand, M. Iida, +8 authors D. L. Wheeler
- Biology, Medicine
- Molecular Cancer Therapeutics
- 14 March 2014
Triple-negative breast cancer (TNBC) is a subclass of breast cancers (i.e., estrogen receptor–negative, progesterone receptor–negative, and HER2-negative) that have poor prognosis and very few… Expand
Mapping C-Terminal Transactivation Domains of the Nuclear HER Family Receptor Tyrosine Kinase HER3
- T. Brand, M. Iida, Neha Luthar, Matthew J Wleklinski, Megan M. Starr, D. L. Wheeler
- Biology, Medicine
- PloS one
- 8 August 2013
Nuclear localized HER family receptor tyrosine kinases (RTKs) have been observed in primary tumor specimens and cancer cell lines for nearly two decades. Inside the nucleus, HER family members (EGFR,… Expand
Reprogramming cell fate with a genome-scale library of artificial transcription factors
- Asuka Eguchi, Matthew J Wleklinski, +12 authors A. Ansari
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 5 December 2016
Significance The ability to convert cells into desired cell types enables tissue engineering, disease modeling, and regenerative medicine; however, methods to generate desired cell types remain… Expand
Molecular and tissue mechanisms of catecholaminergic polymorphic ventricular tachycardia
- Matthew J Wleklinski, P. Kannankeril, B. C. Knollmann
- Medicine
- The Journal of physiology
- 2 March 2020
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a stress‐induced cardiac channelopathy that has a high mortality in untreated patients. Our understanding has grown tremendously since… Expand
An Autosomal Dominant Mutation in Calsequestrin 2 Causes CPVT Without Changing Protein Levels
- Matthew J Wleklinski, Shan S Parikh, B. Knollmann
- Biology
- 15 February 2019
Cancer Biology and Signal Transduction Nuclear Epidermal Growth Factor Receptor Is a Functional Molecular Target in Triple-Negative Breast Cancer
- T. Brand, M. Iida, +8 authors D. L. Wheeler
- 2014
Triple-negative breast cancer (TNBC) is a subclass of breast cancers (i.e., estrogen receptor–negative, progesterone receptor–negative, and HER2-negative) that have poor prognosis and very few… Expand
Abstract 5646: Overcoming acquired resistance to cetuximab by dual targeting of HER family members using antibody based therapy.
- M. Iida, T. Brand, Megan M. Starr, Neha Luthar, Matthew J Wleklinski, D. L. Wheeler
- Medicine
- 15 April 2013
The EGFR is recognized as a key mediator of proliferation and progression in many human tumors and strategies to inhibit EGFR signaling have emerged as highly promising cancer therapy approaches.… Expand
Correction: Nuclear Epidermal Growth Factor Receptor Is a Functional Molecular Target in Triple-negative Breast Cancer
- T. Brand, M. Iida, +8 authors D. L. Wheeler
- Medicine
- Molecular Cancer Therapeutics
- 1 April 2019
Abstract LB-219: Nuclear EGFR serves as a functional molecular target in triple-negative breast cancer.
- T. Brand, M. Iida, Neha Luthar, Matthew J Wleklinski, Kellie T. Kostopoulos, D. L. Wheeler
- Medicine
- 15 April 2013
Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC
Triple negative breast cancer (TNBC) is a subclass of breast cancer (i.e. estrogen receptor negative, progesterone… Expand