Matthew J. Fox

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INTRODUCTION Visual impairment in preterm infants at term equivalent age (TEA) is associated with impaired microstructural development in the optic radiation, measured as reduced fractional anisotropy (FA) by Diffusion Tensor Imaging (DTI). We tested the hypothesis that these abnormalities develop during the late preterm period. METHODS DTI was performed(More)
There is growing interest in exploring fetal functional brain development, particularly with Resting State fMRI. However, during a typical fMRI acquisition, the womb moves due to maternal respiration and the fetus may perform large-scale and unpredictable movements. Conventional fMRI processing pipelines, which assume that brain movements are infrequent or(More)
Reinforced concrete coupled walls are a common lateral load resisting system used in multi-storey buildings. The effect of the coupling beams can improve seismic performance, but at the same time adds complexity to the design procedure. A case study coupled wall building is designed using Force-Based Design (FBD) and Direct Displacement-Based Design (DDBD)(More)
Fetal magnetic resonance imaging (MRI) is now routinely used to further investigate cerebellar malformations detected with ultrasound. However, the lack of 2D and 3D biometrics in the current literature hinders the detailed characterisation and classification of cerebellar anomalies. The main objectives of this fetal neuroimaging study were to provide(More)
PURPOSE The aim of this study was to determine T2* values for the fetal brain in utero and to compare them with previously reported values in preterm and term neonates. Knowledge of T2* may be useful for assessing brain development, brain abnormalities, and for optimizing functional imaging studies. METHODS Maternal respiration and unpredictable fetal(More)
PURPOSE The goal of the Developing Human Connectome Project is to acquire MRI in 1000 neonates to create a dynamic map of human brain connectivity during early development. High-quality imaging in this cohort without sedation presents a number of technical and practical challenges. METHODS We designed a neonatal brain imaging system (NBIS) consisting of a(More)
In the seismic design of structures, capacity design is typically employed to ensure that a desirable ductile response is obtained. In this paper three different capacity design approaches for reinforced concrete coupled walls are investigated. For a simple case study building, the expected capacity design shear forces and bending moments are calculated(More)
This work evaluates the performance of a number of seismic assessment procedures when applied to a case study reinforced concrete (RC) wall building. The performance of each procedure is evaluated through its ability to accurately predict deformation demands, specifically, roof displacement, inter-storey drift ratio and wall curvatures are considered as the(More)
Background Prenatal diagnosis of congenital heart disease is important to ensure both informed parental counselling before birth, and effective planning of potentially life-saving interventions after birth. MRI offers a safe, radiationfree adjunct to conventional diagnostic modalities, particularly in mothers with high BMI or at later gestations where(More)