Matthew Hayman

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Infection by lentiviruses such as human immunodeficiency virus, Maedi-Visna virus and Caprine Arthritis Encephalitis Virus, is associated with a variety of neurological syndromes, but the mechanism by which the damage occurs to the nervous system is not known. The viruses do not infect neurons and so the neurotoxic actions must be mediated indirectly. Here(More)
The function of extraocular muscle proprioception in the control of eye movements remains uncertain. In this study, we examined the effect of bilateral proprioceptive deafferentation of the extraocular muscles on eye movements in two rhesus monkeys. Before and after deafferentation, we analyzed baseline ocular alignment, saccades, pursuit, and vestibular(More)
Ski interacting protein (Skip) has been found to bind to the highly conserved region of Ski, which is required for its transforming activity. Ski is a unique oncoprotein that is involved in inducing both transformation and differentiation. At the molecular level, Ski has been shown to exhibit either co-activator or co-repressor activity depending on the(More)
Recent physiological experiments in our laboratory suggest that extraocular muscle proprioceptive signals are involved in oculomotor control in the pigeon [e.g., Knox and Donaldson (1993) Proc. R. Soc. Lond. B 253, 77-82]; the present results provide information about the primary afferent pathway involved in these actions. In other physiological experiments(More)
Movements of the head and eyes are known to be intimately related. Eye position has also been shown to be closely related to the electromyographic activity of dorsal neck muscles; however, extraocular muscle proprioception has not generally been considered to play a part in the control of such movements. We have previously shown that, in the pigeon, imposed(More)
A field-deployable water vapor profiling instrument that builds on the foundation of the preceding generations of diode-laser-based differential absorption lidar (DIAL) laboratory prototypes was constructed and tested. Significant advances are discussed, including a unique shared telescope design that allows expansion of the outgoing beam for eye-safe(More)
A bathymetric, polarization lidar system transmitting at 532 nm and using a single photomultiplier tube is employed for applications of shallow water depth measurement. The technique exploits polarization attributes of the probed water body to isolate surface and floor returns, enabling constant fraction detection schemes to determine depth. The minimum(More)
Movements of the head and eye which, together, result in changes in the direction of gaze are linked in a number of species, including man, and eye position is known to affect the activity of neck muscles. This head-eye linkage has generally been ascribed to modification of neck muscle activity by internal estimates of eye position derived from motor(More)
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