Matthew Hagan

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PURPOSE: The hypoxia-signaling pathway regulates endochondral ossification, and is critically important for proper modulation of inflammation, angiogenesis, and osteogenesis following trauma. Although hypoxia inducible factor-1α (Hif-1α) and hypoxia inducible factor-2α (Hif2α) are critical mediators of this pathway, the role of these factors in fracture(More)
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