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We utilize effective algorithms for computing in the cohomology of a Shimura curve together with the Jacquet-Langlands correspondence to compute systems of Hecke eigenvalues associated to Hilbert modular forms over a totally real field F. The design of algorithms for the enumeration of automorphic forms has emerged as a major theme in computational(More)
Leptin regulates body weight by signaling to the brain the availability of energy stored as fat. This negative feedback loop becomes disrupted in most obese individuals, resulting in a state known as leptin resistance. The physiological causes of leptin resistance remain poorly understood. Here we test the hypothesis that hyperleptinemia is required for the(More)
The relationship between expression of receptors for oestrogen and progesterone (ER and PR) and disease progression in breast cancer was investigated by comparing immunocytochemical determinations of ER and PR in fine needle aspirates from primary and secondary breast tumours. Rates of receptor expression were significantly higher in primary than in(More)
We define a cocycle on GL n (Q) using Shintani's method. This construction is closely related to earlier work of Solomon and Hill, but differs in that the cocycle property is achieved through the introduction of an auxiliary perturbation vector Q. As a corollary of our result we obtain a new proof of a theorem of Diaz y Diaz and Friedman on signed(More)