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  • Christopher J Phiel, Fuming Zhang, Eric Yi-Hsiu Huang, Matthew G. Guenther, Mitchell A. Lazar, Peter S Klein
  • Biology, Medicine
  • The Journal of Biological Chemistry
  • 2001 (First Publication: 28 September 2001)
  • Valproic acid is widely used to treat epilepsy and bipolar disorder and is also a potent teratogen, but its mechanisms of action in any of these settings are unknown. We report that valproic acidExpand
  • Matthew G. Guenther, William Arbuthnot Sir Lane, Wolfgang Fischle, Eric Verdin, Mitchell A. Lazar, Ramin Shiekhattar
  • Biology, Medicine
  • Genes & development
  • 2000 (First Publication: 1 May 2000)
  • The corepressor SMRT mediates repression by thyroid hormone receptor (TR) as well as other nuclear hormone receptors and transcription factors. Here we report the isolation of a novel SMRT-containingExpand