Matthew Friedrichsen

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Lymphoid organ hypertrophy is a hallmark of localized infection. During the inflammatory response, massive changes in lymphocyte recirculation and turnover boost lymphoid organ cellularity. Intriguingly, the exact nature of these changes remains undefined to date. Here, we report that hypertrophy of Salmonella-infected Peyer's patches (PPs) ensues from a(More)
Increased expression of the inhibitory G protein Gi alpha-2 is assumed to contribute to desensitization of adenylyl cyclase in human heart failure. The mechanisms of upregulation involve increases in myocardial Gi alpha-2 protein, mRNA and gene transcriptional activity. To elucidate these mechanisms in more detail, the 5' flanking region of the human Gi(More)
We investigate the structure of a function relevant to cryptography, given by f : x 7→ x mod p, for p a prime. We call f the self-power map. Given x, it is easy to calculate f(x) ≡ x (mod p). However, it is thought to be difficult to quickly calculate f−1(xx). That is, given x ≡ c (mod p), for a fixed c, it is difficult to quickly solve for x. We call the(More)
Increased expression of the inhibitory G protein Giα-2 is assumed to contributed to desensitization of adenylyl cyclase in human heart failure. The mechanisms of upregulation involve increases in myocardial Giα-2 protein, mRNA and gene transcriptional activity. To elucidate these mechanisms in more detail, the 5′ flanking region of the human Giα-2 gene(More)
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