Matthew Fletcher

Christian Pustelny1
Aravindan Ilangovan1
Siri Ram Chhabra1
Wiener-Rogers Law1
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Bacterial populations co-ordinate gene expression collectively through quorum sensing (QS), a cell-to-cell communication mechanism employing diffusible signal molecules. The LysR-type transcriptional regulator (LTTR) protein PqsR (MvfR) is a key component of alkyl-quinolone (AQ)-dependent QS in Pseudomonas aeruginosa. PqsR is activated by(More)
  • Matthew Fletcher, Maria E Ramirez, Rosa Sierra, Patrick Raber, Paulo Rodriguez
  • 2013
Recent studies have suggested the relevance of different energy metabolic pathways in the balance between protective T cell immunity and T cell anergy in tumors. We and others have suggested the role of the depletion of the non-essential amino acid L-arginine as a mechanism for the induction of T cell suppression in tumors. Therefore, we hypothesize that it(More)
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