Matthew E Spector

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OBJECTIVE Document a case of bilateral otosclerosis with coexisting bilateral superior semicircular canal dehiscence syndrome and the treatment of hearing loss in this setting. PATIENT A 33-year-old woman presented with bilateral mixed hearing loss; worse in the left ear. This was gradual in onset, and she denied dizziness. Computerized tomographic scan(More)
OBJECTIVE To provide an up-to-date review of treatment and outcomes of patients with squamous cell carcinoma (SCCA) involving the temporal bone. DESIGN Retrospective cohort study of all patients treated at our institution for SCCA of the temporal bone between 1995 and 2007 with follow-up until 2011. Factors evaluated were demographics, presenting(More)
BACKGROUND Despite better prognosis, there is a group of oropharyngeal squamous cell carcinoma (SCC) human papillomavirus (HPV)+ patients who experience treatment failure and succumb to distant metastasis. METHODS Seventy-eight previously untreated patients nested in a concurrent chemoradiation protocol were reviewed to correlate patterns of(More)
Laryngeal squamous cell carcinoma (LSCC) remains a highly morbid and fatal disease. Historically, it has been a model example for organ preservation and treatment stratification paradigms. Unfortunately, survival for LSCC has stagnated over the past few decades. As the era of next-generation sequencing and personalized treatment for cancer approaches, LSCC(More)
OBJECTIVES This is a case report on tracheobronchial amyloidosis. This disease may provide a diagnostic challenge for otolaryngologists due to its rarity and relative lack of literature. Our case highlights presentation and workup of this disease. METHODS The index patient's workup included clinical exam, CT of the neck and chest, direct laryngoscopy,(More)
HNSCC that involves the skin is able to invade the dermal lymphatic system. Currently there is no way to identify patients with dermal lymphatic invasion preoperatively. The purpose of this study is to determine whether CT can predict dermal lymphatic invasion. Medical records, CT scans, and corresponding histopathologic slides were reviewed of HNSCC(More)
OBJECTIVE Discussion of a rare case of angioleiomyoma of the internal auditory canal. PATIENT Thirteen-year-old female patient with a 1-year history of progressive hearing loss. INTERVENTION Middle cranial fossa approach providing complete surgical extirpation. MAIN OUTCOME MEASURE Surgical pathology. RESULTS Radiography and history suggestive of(More)
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