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The Pathway Interaction Database (PID, http://pid.nci.nih.gov) is a freely available collection of curated and peer-reviewed pathways composed of human molecular signaling and regulatory events and key cellular processes. Created in a collaboration between the US National Cancer Institute and Nature Publishing Group, the database serves as a research tool… (More)
The majority of digital games available today offer a variety of multi-player settings including co-located and mediated play between opponents. Immersion, the sense of being " in the game, " is one of the key components of the gaming experience but existing literature suggests that social play provides more fun but less immersion. There is however little… (More)
We study the complex of partial bases of a free group, which is an analogue for Aut(Fn) of the curve complex for the mapping class group. We prove that it is connected and simply connected, and we also prove that its quotient by the Torelli subgroup of Aut(Fn) is highly connected. Using these results, we give a new, topological proof of a theorem of Magnus… (More)
The Birman exact sequence describes the effect on the mapping class group of a surface with boundary of gluing discs to the boundary components. We construct an analogous exact sequence for the automorphism group of a free group. For the mapping class group, the kernel of the Birman exact sequence is a surface braid group. We prove that in the context of… (More)
The Alliance for Cellular Signaling (AfCS)-Nature Molecule Pages will be a comprehensive database of key facts about more than 3,000 proteins involved in cell signalling. Each entry will be created by invited experts and be peer-reviewed. Alongside the large-scale experiments being conducted by the AfCS scientists, the wealth of information contained in… (More)
In this paper, we describe a simple system to recognize emotions from short video sequences, developed for the Emotion Recognition in the Wild Challenge (EmotiW 2013). Performance matches the challenge baseline whilst being significantly faster and lower in complexity. Our experiments and subsequent discussion provide a number of insights into the problem.
Let IA n be the Torelli subgroup of AutpF n q. We give an explicit finite set of generators for H 2 pIA n q as a GL n pZq-module. Corollaries include a version of surjective representation stability for H 2 pIA n q, the vanishing of the GL n pZq-coinvariants of H 2 pIA n q, and the vanishing of the second rational homology group of the level ℓ congruence… (More)
We develop an analogue of the Birman exact sequence for the Torelli subgroup of AutpF n q. This builds on earlier work of the authors who studied an analogue of the Birman exact sequence for the entire group AutpF n q. These results play an important role in the authors' recent work on the second homology group of the Torelli group.
13 The Health Industry Forum is based at Brandeis University, chaired by Professor Stuart Altman, and directed by Robert Mechanic. The Forum brings together public policy experts and senior executives from leading healthcare organizations to address challenging health policy issues. The Forum conducts independent, objective policy analysis and provides… (More)
The effectiveness of the cascaded object detector has been demonstrated repeatedly, and the basic steps to generate one are well known. But it is not obvious how to ensure the resulting detector will be efficient. This paper offers a solution by introducing a performance criterion that combines detection rate, false positive rate and speed, and a new cost… (More)