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Centrosomes were microsurgically removed from BSC-1 African green monkey kidney cells before the completion of S phase. Karyoplasts (acentrosomal cells) entered and completed mitosis. However, postmitotic karyoplasts arrested before S phase, whereas adjacent control cells divided repeatedly. Postmitotic karyoplasts assembled a microtubule-organizing center(More)
An automatic left ventricle (LV) segmentation algorithm is presented for quantification of cardiac output and myocardial mass in clinical practice. The LV endocardium is first segmented using region growth with iterative thresholding by detecting the effusion into the surrounding myocardium and tissues. Then the epicardium is extracted using the active(More)
UNLABELLED This retrospective analysis of existing patient data had institutional review board approval and was performed in compliance with HIPAA. No informed consent was required. The purpose of the study was to develop and validate an algorithm for automated segmentation of the left ventricular (LV) cavity that accounts for papillary and/or trabecular(More)
OBJECTIVE The objectives of this study were to prospectively evaluate changes in tumor perfusion after chemoradiation therapy and to investigate the feasibility of perfusion CT for prediction of early tumor response and prognosis of non-small cell lung cancer. SUBJECTS AND METHODS Perfusion CT was performed on an MDCT scanner with 50 mL of iodinated(More)
PURPOSE To evaluate the clinical performance of a novel automated left ventricle (LV) segmentation algorithm (LV-METRIC) that involves no geometric assumptions. MATERIALS AND METHODS LV-METRIC and manual tracing (MT) were used independently to quantify LV volumes and LVEF (ejection fraction) for 151 consecutive patients who underwent cine-CMR(More)
OBJECTIVES The aim of this study was to assess the relationship of the extent of subclinical atherosclerosis measured by coronary artery calcification (CAC) to the extent of second-hand tobacco smoke (SHTS) exposure in asymptomatic people who never smoked. BACKGROUND An association between SHTS and CAC was recently reported in a single study, but the(More)
PURPOSE To assess the usefulness of ordinal scoring of the visual assessment of coronary artery calcification (CAC) on low-dose computed tomographic (CT) scans of the chest in the prediction of cardiovascular death. MATERIALS AND METHODS All participants consented to low-dose CT screening according to an institutional review board-approved protocol. The(More)
OBJECTIVES This study sought to compare contrast-enhanced anatomic imaging and contrast-enhanced tissue characterization (delayed-enhancement cardiac magnetic resonance [DE-CMR]) for left ventricular (LV) thrombus detection. BACKGROUND Contrast echocardiography (echo) detects LV thrombus based on anatomic appearance, whereas DE-CMR imaging detects(More)
OBJECTIVE The purpose of this study was to compare whole-heart acquisition with targeted-volume acquisition in 3-T navigator coronary MR angiography with parallel imaging. SUBJECTS AND METHODS The right and left coronary arteries of 20 subjects were imaged with axial whole-heart acquisition and two oblique targeted-volume acquisitions. RESULTS Both(More)
BACKGROUND Left ventricular (LV) mass and ejection fraction are of diagnostic and therapeutic importance in patients with systolic dysfunction. Cardiac MRI (CMR) has been proposed as a standard for these indices. Prior studies have variably included papillary muscles and trabeculae in either intracavitary or myocardial volumes. Quantitative effects and(More)