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Centrosomes were microsurgically removed from BSC-1 African green monkey kidney cells before the completion of S phase. Karyoplasts (acentrosomal cells) entered and completed mitosis. However, postmitotic karyoplasts arrested before S phase, whereas adjacent control cells divided repeatedly. Postmitotic karyoplasts assembled a microtubule-organizing center(More)
OBJECTIVE The objectives of this study were to prospectively evaluate changes in tumor perfusion after chemoradiation therapy and to investigate the feasibility of perfusion CT for prediction of early tumor response and prognosis of non-small cell lung cancer. SUBJECTS AND METHODS Perfusion CT was performed on an MDCT scanner with 50 mL of iodinated(More)
PURPOSE To assess the usefulness of ordinal scoring of the visual assessment of coronary artery calcification (CAC) on low-dose computed tomographic (CT) scans of the chest in the prediction of cardiovascular death. MATERIALS AND METHODS All participants consented to low-dose CT screening according to an institutional review board-approved protocol. The(More)
An automatic left ventricle (LV) segmentation algorithm is presented for quantification of cardiac output and myocardial mass in clinical practice. The LV endocardium is first segmented using region growth with iterative thresholding by detecting the effusion into the surrounding myocardium and tissues. Then the epicardium is extracted using the active(More)
UNLABELLED This retrospective analysis of existing patient data had institutional review board approval and was performed in compliance with HIPAA. No informed consent was required. The purpose of the study was to develop and validate an algorithm for automated segmentation of the left ventricular (LV) cavity that accounts for papillary and/or trabecular(More)
PURPOSE To investigate the effectiveness of flow signal suppression of a motion-sensitizing magnetization preparation (MSPREP) sequence and to optimize a 2D MSPREP steady-state free precession (SSFP) sequence for black blood imaging of the heart. MATERIALS AND METHODS Using a flow phantom, the effect of varying field of speed (FOS), b-value, voxel size,(More)
PURPOSE To evaluate the clinical performance of a novel automated left ventricle (LV) segmentation algorithm (LV-METRIC) that involves no geometric assumptions. MATERIALS AND METHODS LV-METRIC and manual tracing (MT) were used independently to quantify LV volumes and LVEF (ejection fraction) for 151 consecutive patients who underwent cine-CMR(More)
Transthoracic needle biopsy of the indeterminate pulmonary nodule is a well-established, highly accurate, and minimally invasive diagnostic procedure. A pulmonary nodule in virtually any location is accessible to transthoracic needle biopsy. A solid understanding of special biopsy techniques enables the operator to overcome the commonly encountered(More)
RATIONALE AND OBJECTIVES The aim of this study was to compare effective radiation doses between prospective and retrospective electrocardiographic gating during coronary computed tomographic angiography for coronary artery bypass grafting evaluation. MATERIALS AND METHODS Fifty consecutive coronary computed tomographic angiographic exams for coronary(More)
OBJECTIVES The aim of this study was to assess the relationship of the extent of subclinical atherosclerosis measured by coronary artery calcification (CAC) to the extent of second-hand tobacco smoke (SHTS) exposure in asymptomatic people who never smoked. BACKGROUND An association between SHTS and CAC was recently reported in a single study, but the(More)