Matthew C Izegbu

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The effect of the ethanol extract of the rhizome of Zingiber officinale was tested against carbon tetrachloride (CCl(4)) and acetaminophen-induced liver toxicities in rats. Increases in serum and liver marker enzymes such as alanine aminotransferase, aspartate aminotransferase, lactate dehydrogenase, alkaline phosphatase as well as sorbitol and glutamate(More)
Various reports suggest an increasing incidence of breast cancer in Nigeria. The large volume of literature published on the subject of breast cancer bear witness to the interest shown in the subject. We therefore carried out a review of 50 cases of breast cancer recently confirmed histologically by our unit to study their characteristics and compare these(More)
BACKGROUND The incidence of testicular cancers has been increasing in many populations over the past decades and concerns have been expressed about the possible decrease in semen quality in the period. It may account for one of the factors responsible for increasing male infertility in Ilorin, Nigeria. OBJECTIVE To find out the incidence, age distribution(More)
Burns expose the deeper tissues of the skin or body to invasive microbes. Topical preparations for treating burn wounds, to be useful, should ideally have antibiotic power and promote healing. Silver compounds have been the mainstay of topical burn treatment for decades. However, most chemical substances retard wound healing. Several natural agents such as(More)
OBJECTIVE To illustrate the danger of wrong disposal of used dry-cell batteries in Lagos, Nigeria. METHOD Information was extracted from the case notes of a patient who died following the explosion of a 1.5 volt dry-cell battery. No post-mortem was performed because the death certificate was inadvertently issued and the body was buried hurriedly according(More)
Chronic exposure to lead is associated with adverse effects on renal function in laboratory animals and man. There is controversy concerning the direction of change of renal function parameters following chronic lead intoxication. The renal effects of low-dose lead exposure, as opposed to acute and pharmacological doses, require further scrutiny. In order(More)
In clinical setting, uncomplicated diabetes mellitus type 2 is managed with anti-oxidants (e.g. ascorbic acid, alpha-tocopherol, etc.) with standard oral hypoglycaemic agents, which is aimed at limiting its glucose auto-oxidation and lipid peroxidation complications. The current study is an experimental animal study aimed at investigating the effect of(More)
Objectives: This study was conducted to evaluate the histological findings from testicular biopsies in azoospermic men seen at the Lagos State University Teaching Hospital, Ikeja Lagos, Nigeria. Patients and Methods: A retrospective study of testicular biopsies of azoospermic men who presented to our institution from 2005 to 2006 was performed. The(More)
The case reported is that of a communications technician admitted to hospital with 38% burns sustained while climbing a communications mast. The mast was erected less than 3 metres from a 33 kv electric transmission cable. His condition is described, as also the treatment he received until his discharge three months later. In the absence of guidelines(More)
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