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Chronic lung disease in prematurely born infants, defined as the need for increased inspired oxygen at 28 days of age, was thought to be more common in some institutions than in others. To test this hypothesis, we surveyed the experience in the intensive care nurseries at Columbia and Vanderbilt Universities, the Universities of Texas at Dallas, Washington(More)
We investigated repetitive and stereotyped behavior (RSB) and its relationship to morphometric measures of the basal ganglia and thalami in 3- to 4-year-old children with autism spectrum disorder (ASD; n = 77) and developmental delay without autism (DD; n = 34). Children were assessed through clinical evaluation and parent report using RSB-specific scales(More)
Congenital central hypoventilation (Ondine's curse) is described in an infant with persistant symptoms throughout the first nine months of life. Respiratory control was most severely affected in quiet sleep, although abnormalities were present in rapid eye movement (REM) sleep and while awake. Failure of metabolic control in quiet sleep led to profound(More)
The feasibility of high-frequency oscillatory ventilation was investigated in eight neonates with severe RDS. Low-volume, high-frequency flow oscillations were generated by a piston pump and delivered through standard endotracheal tubes. Oscillatory frequencies ranged from 8 to 20 Hz and mean airway pressure from 9 to 20 cm H2O. Heart rate, airway(More)
The lactose, lipid, protein, and total energy content of milk produced during the first 4 wk of lactation was determined in milk from mothers giving birth prematurely and at term. Milk samples analyzed were representative of complete 24-h expressions. Over the first 4 wk of lactation lactose concentration increased, but nitrogen concentration decreased by(More)
The importance of inspiratory muscle tone in the maintenance of functional residual capacity (FRC) in newborns was studied in eight premature infants with birth weights of 1,166 +/- 217 g and gestational age 29 +/- 1.9 wk (mean +/- SD). Rib cage and abdominal anteroposterior diameters were monitored with magnetometers, and electromyograms of the diaphragm(More)
Academic achievement patterns and their relationships with intellectual ability, social abilities, and problem behavior are described in a sample of 30 higher-functioning, 9-year-old children with autism spectrum disorder (ASD). Both social abilities and problem behavior have been found to be predictive of academic achievement in typically developing(More)
Complete 24-hour expressions of milk were collected over the first month of lactation from mothers giving birth at term (FT) and prematurely (PT). Samples were analyzed for Cu, Fe and Zn concentration. Composition of PT and FT milks was similar during the first 4 weeks of lactation, but the concentrations of each mineral were higher during the first week(More)
During a 22-year period, 12 cases of spontaneous chylothorax in newborns were diagnosed at a large pediatric tertiary care center. Seven infants had right-sided effusions; only one effusion occurred on the left. Severe bilateral accumulations occurred in four nonimmune hydropic premature infants. The diagnosis was made by the milky appearance and/or the(More)