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The organization of the efferent projections from the pontine parabrachial (pPB) area to the amygdala has been studied in the rat by using microinjections of Phaseolus vulgaris leucoagglutinin (PHA-L), a sensitive and selective anterograde axonal marker, into restricted subregions of the pPB area. The results confirmed that the pPB area primarily projected(More)
The organization of efferent projections from the pontine parabrachial (pPB) area to the forebrain rostral to the central nucleus of the amygdala (Ce) was studied in the rat by using microinjections of Phaseolus vulgaris leucoagglutinin (PHA-L), into subregions of the pPB area. The present study is a follow-up of a former study (Bernard et al. [1993] J.(More)
To be able to achieve security assurance for services, which run on large and complex communication infrastructures, support tools are needed. Such tools need a representations of the infrastructure that enables and provides security assurance. In this paper we suggest an assurance modeling profile for UML 2.0. The profile contains stereotypes that define(More)
Estimation of Distribution Algorithms (EDAs) combine genetic algorithms with statistical modeling in order to learn and exploit the structure of search domains. Such algorithms work well when the EDA's statistical model matches the structure of the domain. Many EDAs use statistical models that represent domain structure with directed acyclic graphs (DAGs).(More)
In this paper we introduce The Eugenic Algorithm with Modeling (TEAM), an evolutionary search algorithm that employs statistical analysis to promote construction of high-fitness chromosomes. A model of gene/fitness correlations is automatically generated to direct the construction process. When applied to the combinatorial optimization problems of finding a(More)
OBJECTIVE The study evaluated whether the average performance of clubhouses certified by the International Center for Clubhouse Development (ICCD) should be considered valid benchmarks for clubhouse programs. METHODS A representative sample of clubhouses more than three years old that were based on the Fountain House model participated in a 1998 mail(More)
The multifaceted complexity of real-time strategy (RTS) games forces AI systems to break down policy computation into smaller subproblems – strategic planning, tactical planning, reactive control , and others. To further simplify planning at the strategic and tactical levels, state-of-the-art automatic techniques for this task, such as case-based planning,(More)
This is to certify that I have examined this copy of a master's thesis by Aparna Sundara Rajan and have found that it is complete and satisfactory in all respects, and that any and all revisions required by the final examining committee have been made. Date: Extensive copying of this demonstration thesis, including its input files and macro package, is(More)
GI147211 is a novel, totally synthetic camptothecin with promising preclinical and early clinical activity. This study was designed to determine the maximum tolerated dose of Gl147211 as a 72-h infusion and to describe its pharmacokinetics and pharmacodynamics on this schedule. In a single-arm, rising-dose study in patients with advanced cancer, eight(More)
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