Matteo Appolloni

Learn More
Lysosomal alpha-d-mannosidase from mouse tissues was separated into its constituent isoenzymes by DEAE-cellulose chromatography. Forms corresponding to the human isoenzymes B and A were present in testis, brain, spleen and kidney, whereas in epididymis and liver only the B form was present. Murine alpha-mannosidases A and B are glycoproteins and have pH(More)
The GM2 activator protein is an essential component for the degradation of GM2 ganglioside by hexosaminidase A in vivo. Mutations in the human gene coding for the GM2 activator protein cause the AB variant of GM2-gangliosidosis, a condition that is clinically indistinguishable from Tay-Sachs disease. To understand better factors affecting the expression of(More)
During launch, a spacecraft undergoes loads ranging from quasi-static to highly transient or harmonic low frequency events, from higher frequency shock loads to acoustic excitations. In order to reproduce such a dynamic diversity, fixed base sinusoidal tests, wide band acoustic loading and different regimes of shock testing are implemented in the test(More)
8. Nakagawa, C., Hanafusa, T., Miyagawa, J., Yutsudo, M., Nakajima, H., Yamamoto, K., Kono, N., Hakura, A., Tarui, S. (1992). Diabetologia 35, 614-618. 9. Tomita, K., Nakajima, H., Hanabusa, T., Miyagawa, J.-l., Iwahashi, H., Yamagake, K., Hamaguchi, T., Kuwashima, M., Matsuzawa, Y., Kono, N., Tanaka, T., Noguchi, T. (1994). Mol. Diabetol. (Japanese) 5,(More)
An ultrastructural and cytochemical analysis of the anterior choroid plexus in adult Rana esculenta was undertaken. The epithelial cells are implicated in the production of cephalorachidian liquid by transporting metabolites from the blood and by synthesizing and secreting activity. The epithelial cells are also capable of re-absorbing catabolites from the(More)
  • 1