Matt Wallace

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The prevalence of ErbB2 amplification in breast cancer has resulted in the heavy pursuit of ErbB2 as a therapeutic target. Although both the ErbB2 monoclonal antibody trastuzumab and ErbB1/ErbB2 dual kinase inhibitor lapatinib have met with success in the clinic, many patients fail to benefit. In addition, the majority of patients who initially respond will(More)
This work presents an offset-free model predictive control (OF-MPC) design for energy efficient control of a heat pump. Open-loop system dynamics are examined first to determine the appropriate control structure leading to identification techniques being used to construct linear models of an experimentally-validated heat pump model. Subsequently, a(More)
The prevalence of ErbB2 amplification in breast cancer has resulted in the heavy pursuit of ErbB2 as a therapeutic target. Although both the ErbB2monoclonal antibody trastuzumab and ErbB1/ErbB2 dual kinase inhibitor lapatinib havemet with success in the clinic, many patients fail to benefit. In addition, themajority of patients who initially respond will(More)
Over the past two decades, mathematics education reformers have increasingly called for new approaches to assessment. This call urges mathematics teachers to merge their assessment with pedagogy, to employ assessments that engage students in the process of "doing mathematics," and to exploit assessment to support learning. This paper presents a research(More)
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