Matt Sabin

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The development of diabetes-related microvascular complications in type 1 diabetes (T1DM) is known to be related to glycaemic control, but the degree to which variations in HbA1c across the lifetime contributes to this risk is unknown. Our hypothesis was that individuals with poor control in childhood and subsequent improved control in adulthood would still(More)
Insulin-like growth factor binding protein-2 (IGFBP-2) is widely abundant in fetal life and remains highly expressed in the brain throughout life. It plays a key role in targeting IGFs to their receptors in developing organs [1]. It is also highly expressed by a broad range of aggressive cancers such that its ablation reduces cancer growth. IGFBP-2 has also(More)
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