Matt DeJongh

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Ontologies are specifications of the concepts in a given field, and of the relationships among those concepts. The development of ontologies for molecular-biology information and the sharing of those ontologies within the bioinformatics community are central problems in bioinformatics. If the bioinformatics community is to share ontologies effectively,(More)
SUMMARY Biology has become an increasingly data-driven science. Modern experimental techniques, including automated DNA sequencing, gene expression micro arrays, and X-ray crystallography are producing molecular data at a rate that has made traditional data analysis methods impractical. Computational methods are becoming an increasingly important aspect of(More)
BACKGROUND Rapid growth in the availability of genome-wide transcript abundance levels through gene expression microarrays and RNAseq promises to provide deep biological insights into the complex, genome-wide transcriptional behavior of single-celled organisms. However, this promise has not yet been fully realized. RESULTS We find that computation of(More)
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