Learn More
Stabilized helical peptides show potential as therapeutics capable of modulating protein function through enhanced helix–protein binding. Helix-turn stabilization may be accomplished though covalent side-chain crosslinking on one face of the helix, in the i and i+4 or i+7 positions, or replacement of a main-chain hydrogen bond with a covalent linker. 5,6](More)
  • 1