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Our recent results show that all-trans retinoic acid (ATRA), an active metabolite of vitamin A, induces COX-dependent hyperalgesia and allodynia in rats. This effect was mediated by retinoic acid(More)
BACKGROUND AND PURPOSE Retinoic acid is an active metabolite of vitamin A involved in the modulation of the inflammatory and nociceptive responses. The aim of the present study was to analyze the(More)
AIMS The aim of this study was to investigate the effects of liver X receptors (LXRs)-β preferential activation by LXR-623 (WAY-252623), a novel LXRs agonist, on plaque progression/regression in a(More)
Objective and design:To study the involvement of all-trans retinoic acid (ATRA) in the development and maintenance of inflammatory pain. Subjects:Adult male Wistar rats and murine neuro2a and human(More)