Mathyam Prabhakar

Learn More
L-asparaginase is an anti-neoplastic agent used in the lymphoblastic leukaemia chemotherapy. In the present study a novel strain, Streptomyces gulbargensis was explored for the production of extra-cellular L-asparaginase using groundnut cake extract. The optimum pH, temperature, inoculum size and agitation speed for enzyme production were pH 8.5, 40°C,(More)
The rice leaf folder, Cnaphalocrocis medinalis Guenée (Lepidoptera: Pyralidae) is a predominant foliage feeder in all the rice ecosystems. The objective of this study was to examine the development of leaf folder at 7 constant temperatures (18, 20, 25, 30, 32, 34, 35° C) and to estimate temperature thresholds and thermal constants for the forecasting models(More)
Five impurities (related substances) were detected during the impurity profile study of an antihypertensive drug substance, valsartan. A simple gradient high performance liquid chromatographic method (HPLC) and liquid chromatography-mass spectrometry (LC-MS) were used for the detection. Based on the spectral data (IR, NMR and MS) followed by synthesis,(More)
The changes in the microbial community structure during acute exacerbations of severe chronic obstructive pulmonary disease (COPD) in hospitalized patients remain largely uncharacterized. Therefore, further studies focused on the temporal dynamics and structure of sputum microbial communities during acute exacerbation of COPD (AECOPD) would still be(More)
Longicorn beetle, Acanthophorus rugiceps Gahan (Coleoptera: Cerambycidae), is reported for the first time as a confirmed host on physic nut, Jatropha curcas L. (Malpighiales: Euphorbiaceae), from India, causing extensive damage to roots. Plants of three years age and above were prone to attack by this pest. In a six year study beginning in 2005, about 11.3(More)
Temperature-driven development and survival rates of the mealybug, Phenacoccussolenopsis Tinsley (Hemiptera: Pseudococcidae) were examined at nine constant temperatures (15, 20, 25, 27, 30, 32, 35 and 40°C) on hibiscus (Hibiscusrosa -sinensis L.). Crawlers successfully completed development to adult stage between 15 and 35°C, although their survival was(More)
Achaea janata granulovirus (AcjaGV), an insect virus belonging to Baculoviridae, infects semilooper, a widely distributed defoliating pest on castor beans (Ricinus communis L.) and several other plant hosts in India. The propagation and purification of the Hyderabad isolate AcjaGV were performed, granulin gene from this isolate was amplified, cloned and(More)
The paper deals with pharmacognosy of Centella asiatica (L.) Urban, including its morphological, anatomical, chemical constituents and powder analysis. Stomata are mostly anisotricytic, isotricytic and few tetracytic. Sphaero-crystals of calcium oxalate are observed in palisade, spongy and ground parenchyma of leaf lamina, petiole and rhizome and absent in(More)
This paper deals with the pharmacognosy of Hyptis suaveolens leaf including its morphological, anatomical, chemical constituents and powder analysis. Contrary to earlier reports, the leaves are amphistomatic. Stomata are diacytic, a few being isotricytic and ansiotricytic. Four types of trichomes have been noted. The venation is semicraspidodromous. Midrib(More)
  • 1