Mathieu Morel

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During development of the nervous system, the tip of a growing axon, the growth cone (GC), must respond accurately to stimuli that direct its growth. This axonal navigation depends on extracellular concentration gradients of numerous guidance cues, including GABA. GCs can detect even weak directional signals, yet the mechanisms underlying this sensitivity(More)
This article describes techniques of vocal forgery able to affect automatic speaker recognition system in a forensic context. Vocal forgery covers two main aspects: voice transformation and voice conversion. Concerning voice transformation, this article proposes an automatic analysis of four specific disguised voices in order to detect the forgery and, for(More)
Difficulties in culturing cells inside microchannels is a major obstacle for the wide use of microfluidic technology in cell biology. Here, we present a simple and versatile method to interface closed microchannels with cellular and multicellular systems. Our approach, based on microfluidic stickers which can adhere to wet glass coverslips, eliminates the(More)
Nerve growth cones (GCs) are chemical sensors that convert graded extracellular cues into oriented axonal motion. To ensure a sensitive and robust response to directional signals in complex and dynamic chemical landscapes, GCs are presumably able to amplify and filter external information. How these processing tasks are performed remains however poorly(More)
We propose a new approach to prepare live cells in a microfluidic environment without cultivating cells in microchannels. We use microfluidic stickers that are tightly sealed over cells, cultured on glass coverslips. By greatly simplifying the conditions in which cells can be placed into a microchip, our method opens new prospects for quantitative(More)
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