Mathieu Laroche

Learn More
Traumatic brain injury has long been associated with abnormal coagulation parameters, but the exact mechanisms underlying this phenomenon are poorly understood. Coagulopathy after traumatic brain injury includes hypercoagulable and hypocoagulable states that can lead to secondary injury by either the induction of microthrombosis or the progression of(More)
Human brain microvascular endothelial cells (HBMECs) play an essential role as structural and functional components of the blood-brain barrier (BBB). While disruption of the BBB by the brain tumor-secreted matrix metalloproteinase-9 (MMP-9) favors tumor invasion, the role and regulation of MMP-9 secretion by HBMEC themselves in response to carcinogens or(More)
Heterodyne optical feedback on a solid-state laser is experimentally investigated as an efficient tool to characterize coherently near-field evanescent waves. A well-known topography of evanescent field is obtained via a total internal reflection of the light beam emitted by a class B Yb:Er glass laser. A subwavelength size optical fiber tip is scanned to(More)
Efficient repetitive passive Q switching of a cladding-pumped Er-Yb fiber laser has been demonstrated by use of an external-cavity configuration containing a Co(2+): ZnS crystal as a saturable absorber. Energies of as much as 60muJ in pulses of durations as short as 3.5 ns (FWHM), corresponding to a peak power of >10kW, have been generated, and the maximum(More)
OBJECTIVE To present a review of the literature and a case series of blood blister-like aneurysms (BBA) to show that an adapted direct surgical approach enables treatment of BBA with a low complication rate. METHODS A retrospective review was performed of patients treated for a ruptured BBA of the internal carotid artery (ICA) at Hôpital Notre-Dame from(More)
We describe an all-fiberized coherent detection system at 1.55 microm using heterodyne self-mixing modulation in a distributed-feedback fiber laser. Frequency shifting of the optical feedback is based on serrodyne phase modulation with an integrated electro-optic modulator, which is a significant advance in the simplification of the self-mixing detection(More)
Distal choroidal artery aneurysms stemming from the lateral wall of the ventricles are rare and are mostly associated with moyamoya disease. The treatment of these aneurysms is difficult because of their deep location. The authors report the case of a 50-year-old woman followed for moyamoya disease presenting with 2 intraventricular hemorrhages. Cerebral(More)
BACKGROUND Use of combination antiretroviral therapy (cART) and cyclophosphamide, doxorubicin, vincristine and prednisone (CHOP) with or without rituximab for treatment of diffuse large B-cell lymphoma (DLBCL) in HIV substantially increases response rates but may also increase toxicity, possibly due to antiretroviral-antineoplastic drug interactions. The(More)
OBJECTIVE This work investigates auditory speech processing in normal listeners through measurement of brainstem responses to the synthetic vowel /a/. METHODS The vowel is presented in quiet and in continuous white noise with different signal-to-noise ratios (SNR) of +5, 0, -5, and -10 dB. RESULTS In the presence of noise, transient response waves V and(More)
Blood blister-like aneurysms (BBA) originate at non-branching sites of the internal carotid artery (ICA). These aneurysms present a fragile wall and a poorly defined broad-based neck. Recognition of the BBA is essential for proper management of these vascular lesions. Various surgical and endovascular strategies have been attempted for these heterogeneous(More)