Mathew Hebert

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Alfuzosin, a selective alpha 1-adrenoceptor antagonist which is effective in the symptomatic treatment of benign prostatic hyperplasia (BPH), was compared with prazosin, another drug commonly used for the same purpose. After a 1-week placebo run-in period, 103 patients with day-time frequency > or = 7 or nocturia > or = 2 and peak flow rate < 15 ml/s were(More)
1. In anaesthetized rats, supramaximal baroreceptor stimulation by carotid sinus inflation evoked a reflex fall in systemic arterial pressure and an increase in gross mesenteric vascular conductance, but no significant change in gross mesenteric blood flow. 2. Principal arteries (80-350 microns internal diameter (i.d.)) which supply the intestine and(More)
1. In anaesthetized rats, supramaximal baroreceptor stimulation by carotid sinus inflation evoked a reflex fall in arterial pressure and an increase in vascular conductance and flow of muscles of the hindquarters. 2. Simultaneously, main arteries, primary and secondary arterioles (13-90 microns, internal diameter (i.d.)) and terminal arterioles (7-13(More)
The intraobserver and interobserver variability of common radiographic measurements associated with hip dysplasia from plain and digital radiographs was assessed. Only the interobserver reliability of measuring Hilgenreiner's distance was found to be potentially clinically significant. The average Spearman correlation coefficients between groups were 0.81(More)
The responses of mesenteric microcirculation of the rat to circulating noradrenaline were studied by in vivo microscopy, using a photo-electric device placed on a television monitor to measure changes in diameter of individual vessels. Blood flow was measured in the anterior mesenteric artery with an electromagnetic flow transducer, mesenteric vascular(More)