Mathew D Johnson

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BACKGROUND The motor thalamus is a key nodal point in the pallidothalamocortical "motor" circuit, which has been implicated in the pathogenesis of Parkinson's disease (PD) and other movement disorders. Although a critical structure in the motor circuit, the role of the motor thalamus in mediating the therapeutic effects of deep brain stimulation (DBS) of(More)
Neurophysiological changes in the basal ganglia thalamo-cortical circuit associated with the development of parkinsonian motor signs remain poorly understood. Theoretical models have ranged from those emphasizing changes in mean discharge rate to increased oscillatory activity within the beta range. The present study characterized neuronal activity within(More)
EEP brain stimulation (DBS) has been successfully used to treat an increasing number of neurological disorders. While new therapies are continuously being investigated, the lead itself has remained relatively unchanged. In contrast, auditory neuroprostheses such as the cochlear implant (CI) or the auditory midbrain implant (AMI) have been continuously(More)
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