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1. Rhodopsin has been measured by Rushton's method of reflexion densitometry in a retinal region 18 degrees temporal to the fovea, using a wavelength of measuring light (555 nm) so far into the long wave part of the spectrum that possible blue absorbing intermediates (e.g. transient orange) do not interfere.2. Rhodopsin was bleached by a strong light for 10(More)
1. The fraction of red in a red--green mixture matched to yellow increased as the intensities of the match constituents were increased sufficiently to bleach appreciable chlorolabe and erythrolabe. 2. All changes in matching found for a given normal trichromat, (i) with increase in the intensities of the matching components, (ii) as a function of time after(More)
Foveal threshold elevation and red-green cone pigment regeneration have been studied in the dark after a wide range of bleaches in normal man with a view to probing the limits of the application of the Dowling-Rushton relation: i.e., the direct proportionality between log threshold elevation and fraction of unregenerated pigment. Cone pigment regeneration(More)
Microspectrophotometry (MSP) shows rhodopsin highly concentrated (about 3.0 mmol/l) in rod outer segments (ROS). Calculation of the in vivo absorption spectrum of human rhodopsin from such data reveals a striking failure to agree with the action spectrum of human rod vision. Agreement is good between the spectral distribution of absorption coefficients and(More)
1. The visual pigment in a 5 degrees circular patch of the living human retina 18 degrees temporal from the fovea was studied with the Rushton retinal densitometer. The measuring light (570 nm) was selected to obviate artifacts from colour photoproducts.2. The action spectrum of a 10% bleach agrees well with the action spectrum at absolute threshold for the(More)
The unilateral tritanope described in the previous paper (Alpern, Kitahara & Krantz, 1983) was able to match every narrow-band light presented to his tritanopic eye with lights from a tristimulus colorimeter viewed in the adjacent field by the normal eye. In two regions of the spectrum (called isochromes) physically identical lights appeared identical to(More)
Measurements have been made of the magnitude of simultaneous brightness contrast on two young adult male observers by a binocular brightness matching method. Five different luminances of the inducing pattern were studied and the duration of the exposure was varied between 5 and 150 msec, along an arithmetic scale. For low inducing flash luminances, the(More)
1. This investigation is based upon Alpern's (1965) contrast flash observations. The threshold for the test flash lambda (Fig. 2a) is raised if a second flash varphi falls on the annular surround. Moreover, if lambda excites rods at threshold, it is only the rods in the surround that contribute to the threshold rise.2. The possibility that the rise in(More)