Mateusz Banaszczyk

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Stabilization of poly-L-lysine/DNA polyplexes for in vivo gene delivery to the liver.

D. Y. Kwoh, Caroline Coffin, +9 authors D J Carlo
Biochimica et biophysica acta
1999

We are developing a self-assembling non-viral in vivo gene delivery vehicle based on poly-l-lysine and plasmid DNA. We have characterized poly-l-lysines of different chain lengths for DNA… (More)

Obstacles and advances in non-viral gene delivery.

Charles P Lollo, Mateusz Banaszczyk, H. C. Chiou
Current opinion in molecular therapeutics
2000

This review focuses on recent progress and novel strategies to improve the efficiency of in vivo non-viral gene delivery. Examples of the most promising attempts to overcome specific barriers are… (More)

Strength of conjugate binding to plasmid DNA affects degradation rate and expression level in vivo.

Paul M. Mullen, Charles P Lollo, +8 authors D J Carlo
Biochimica et biophysica acta
2000

In vitro assays have demonstrated the capability of poly-L-lysine to protect plasmid DNA from serum nucleases and cellular lysates. Our purpose was to evaluate the stability and potency of… (More)

The Failure in the Stabilization of Glioblastoma-Derived Cell Lines: Spontaneous In Vitro Senescence as the Main Culprit

Ewelina Stoczyńska-Fidelus, Sylwester Piaskowski, +9 authors Piotr Rieske
PloS one
2014

Cell line analysis is an important element of cancer research. Despite the progress in glioblastoma cell culturing, the cells isolated from the majority of specimens cannot be propagated infinitely… (More)

HIV prevalence at reception into Australian prisons, 1991-1997.

A. M. McDonald, John Ryan, +7 authors Jonathan M. Kaldor
The Medical journal of Australia
1999

OBJECTIVE To measure the extent and outcome of HIV antibody testing at reception into Australian prisons. DESIGN Cross-sectional survey at reception into prison. PARTICIPANTS AND SETTING People… (More)

Screening for EGFR Amplifications with a Novel Method and Their Significance for the Outcome of Glioblastoma Patients

Michał Bieńkowski, Sylwester Piaskowski, +11 authors Pawel Liberski
PloS one
2013

Glioblastoma is a highly aggressive tumour of the central nervous system, characterised by poor prognosis irrespective of the applied treatment. The aim of our study was to analyse whether the… (More)

Cell line with endogenous EGFRvIII expression is a suitable model for research and drug development purposes

Wojciech J. Stec, Kamila Rosiak, +9 authors Piotr Rieske
Oncotarget
2016

Glioblastoma is the most common and malignant brain tumor, characterized by high cellular heterogeneity. About 50% of glioblastomas are positive for EGFR amplification, half of which express… (More)

EGFR Activation Leads to Cell Death Independent of PI3K/AKT/mTOR in an AD293 Cell Line

Cezary Treda, Marta Popęda, +6 authors Piotr Rieske
PloS one
2016

The Epidermal Growth Factor Receptor (EGFR) and its mutations contribute in various ways to tumorigenesis and biology of human cancers. They are associated with tumor proliferation, progression, drug… (More)

Glioblastoma specimens with TP53 mutations do not show EGFRvIII amplification.

Ewelina Stoczyńska-Fidelus, Monika Witusik-Perkowska, +8 authors Piotr Rieske
Cancer genetics
2011

Watanabe et al. described TP53 mutation and epidermal growth factor receptor (EGFR) amplification as being mutually exclusive (1). In 2003, however, Okada et al. (2) showed that peripheral or local… (More)

Limited importance of the dominant-negative effect of TP53 missense mutations

Ewelina Stoczyńska-Fidelus, Malgorzata Szybka, +8 authors Piotr Rieske
BMC Cancer
2010

Heterozygosity of TP53 missense mutations is related to the phenomenon of the dominant-negative effect (DNE). To estimate the importance of the DNE of TP53 mutations, we analysed the percentage of… (More)

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