Massimo De Napoli

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The aim of the present investigation was to study the effects of choline and choline-containing phospholipids CDP-choline (CDPC) and L-alpha-glyceryl-phosphorylcholine (AGPC) on transglutaminase (TG) activity and expression in primary astrocyte cultures. TG is an important Ca(2+)-dependent protein that represents a normal constituent of nervous systems(More)
Laboratory screening of a series of halogenated methyl isopropyl ethers revealed sevoflurane (fluoromethyl-1,1,1,3,3,3,-hexafluroro-2-propyl ether) as a potent nonexplosive inhalational anesthetic agent. Sevoflurance, a pleasant-smelling liquid, boils at 58.5 degrees C at 760 torr and has a vapor pressure of 200 torr at 25 degrees C. It is nonflammable in(More)
Lipoic acid plays a crucial role as antioxidant and metabolic component of enzymes involved in glucose metabolism of different cell types. Choline alphoscerate (α-glyceryl-phosphoryl-choline [αGPC]) is a semisynthetic derivative of phosphatidylcholines representing, among acetilcholine precursors, a cholinergic drug. In the present study, we evaluated the(More)
DNA is a polymorphic polymer that can adopt a variety of secondary structures ranging from the canonical right-handed B form to the left-handed Z conformation. The latter conformation is less common than the right-handed B-DNA because under physiological conditions Z-DNA has a higher energy. Although the biological role of Z-DNA still remains to be(More)
Silicon carbide (SiC) Schottky diodes 21 μm thick with small surfaces and high N-dopant concentration have been used to detect alpha particles and low energy light ions. In particular C and O beams at incident energies between 5 and 18 MeV were used. The diode active-region depletion-thickness, the linearity of the response, energy resolution and signal(More)
BACKGROUND The association between diverticulosis and colonic neoplastic lesions has been suggested, but data in literature are conflicting. This study aimed to investigate such a relationship in patients participating in a colorectal cancer screening program who underwent high-quality colonoscopy. METHODS Data from consecutive individuals 50-75 years of(More)
INFN — Laboratori Nazionali del Sud, Catania, Italy Dipartimento di Fisica e Astronomia, Università degli studi di Catania, Italy INFN — Sezione di Catania, Italy Department of Physics, University of Oslo, Norway INFN — Laboratori Nazionali del Gran Sasso, Italy Nuclear and Radiation Physics Section Katholieke Universiteit Leuven, Heverlee, Belgium(More)