Massimo Conti

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BACKGROUND Diagnosis of malignant pleural mesothelioma is a challenging issue. Potential markers in mesothelioma diagnosis include soluble mesothelin-related peptides (SMRPs) and osteopontin, but no subsequent validation has been published yet. METHODS We prospectively evaluated SMRPs in serum and pleural effusion from patients with mesothelioma (n = 74),(More)
OBJECTIVE This study was undertaken to determine factors associated with in-hospital mortality among patients after general thoracic surgery and to construct a risk model. METHODS Data from a nationally representative thoracic surgery database were collected prospectively between June 2002 and July 2005. Logistic regression analysis was used to predict(More)
STUDY OBJECTIVES To determine whether nonoperative management can be applied to iatrogenic postintubation tracheobronchial rupture (TBR). DESIGN Prospective cohort study. PATIENTS AND INTERVENTIONS Thirty consecutive patients with TBR complicating intubation between June 1993 and December 2005 entered the study. Patients not receiving mechanical(More)
The concept of a SOC platform architecture introduces the concept of a communication infrastructure. In the transaction-level a finite set of architecture components (memories, arithmetic units, address generators, caches, etc) communicate among each other over shared resources (buses). Until recently, modeling architectures required pin-level hardware(More)
Bus performances are extremely important in a platform-based design. System Level analysis of bus performances gives important information for the analysis and choice between different architectures driven by functional, timing and power constraints of the System-on-Chip. This paper presents the effect of different arbitration algorithms and bus usage(More)
Thymomas are low-grade epithelial cancers of the thymus whose prevalence varies between 0.1/100,000 and 0.4/100,000. Familial occurrence of thymoma is very rare. We studied a family bearing the constitutional chromosome translocation t(14;20)(q24;p12), 3 of whose members had a thymoma. In this family, among 27 patients, 11 had the translocation: 3 had(More)
BACKGROUND Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) play a role in the processes of extracellular matrix degradation. Changes in their expression levels have been observed in various tumor types, including lung carcinoma. However, their clinical significance and their prognostic importance in the progression of(More)
BACKGROUND This study was designed to assess the early and long-term results, and determine suitable indications of anterior mediastinal tracheostomy, after radical resection for cervicothoracic malignancies. METHODS From 1985 to 2009, 13 patients ranging in age from 40 to 75 years underwent an anterior mediastinal tracheostomy for malignancy, 2 as an(More)
RATIONALE Previous data suggested that serum levels of soluble mesothelin (SM) are related to tumor size and may have prognostic significance in malignant pleural mesothelioma (MPM). OBJECTIVES We tested the hypothesis that this marker could also be useful for monitoring response to treatment. METHODS Serial measurements of SM were determined in 40(More)
Cardiovascular autonomic dysfunction can occur in Parkinson's disease (PD) and intracranial vascular modifications following orthostatism may be relevant to diagnostic and therapeutic decision-making. We performed transcranial Doppler monitoring of right middle cerebral artery (MCA) at rest and during passive 70 degrees tilt in 19 patients with idiopathic(More)