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BACKGROUND Autistic individuals often exhibit hyperarousal behaviors (e.g., stereotyped body movements, self-stimulation, hypervigilance, and hyperactivity). Clonidine, an alpha 2-adrenergic receptor agonist, has been shown to be effective in reducing impulsivity, inattention, and hyperactivity associated with attention deficit disorder with hyperactivity.(More)
Video games capture the rapt attention of an individual player's mind and body, providing new opportunities for personalized health care. An example of therapeutic interactive technologies is an incentive-based video game that translates physical exercise into mental empowerment via motivational metaphoric visualization in order to help patients(More)
Pediatric oncology patients often experience fatigue and physical and mental deconditioning during and following chemotherapy treatments, contributing to diminished quality of life. Patient empowerment is a core principle of patient-centered care and reflects one's ability to positively affect his or her own health behavior and health status. Empowerment(More)
The short and long-term effects of a parent-infant training program for biologically handicapped infants was evaluated in terms of maternal locus of control. Twenty-four infants were evaluated on five developmental scales measuring motor, cognitive, and language functioning over a four-year period. Developmental gains on these indices were regressed against(More)
Behavioral rating scales commonly used in efficacy studies of antianxiety and antidepressant drugs are described, and the appropriate use of these scales in clinical studies is discussed from the perspective of pharmacists who must evaluate such studies. Defined first are four attributes by which all rating scales are developed and evaluated:(More)
Vertebrate retinal development is a complex process, requiring the specification and maintenance of retinal identity, proliferative expansion of retinal progenitor cells (RPCs), and their differentiation into retinal neurons and glia. The homeobox gene Vsx2 is expressed in RPCs and required for the proper execution of this retinal program. However, our(More)
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