Masoud Saghafi

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AIM The reduced bone density in individuals with severe hemophilia A (decreased coagulation factor VIII level) and combined factor V and VIII deficiency have been reported. In the current case-control study we tried to address bone mineral density in individuals with severe hemophilia B (decreased coagulation factor IX). METHODS In our case-control study,(More)
AIM Vitamin K is an essential factor for carboxylation of bone matrix protein. Low vitamin K may be associated with reduced bone mineral density (BMD). The issue of whether long-term sodium warfarin therapy as oral anticoagulant that antagonizes vitamin K, results in decreased bone density, is controversial. Our purpose in this study was to assess the(More)
Background Cathelicidin (LL-37), an endogenous antimicrobial peptide, has recently been involved in the pathogenesis of autoimmune diseases. To assess whether LL-37 reflects disease activity, we measured serum levels of it in systemic lupus erythematosus (SLE) patients with active and inactive disease compared to healthy controls. LL-37 was also compared(More)
Background: The most effective treatment in chemical warfare victims (CWV) suffering from severe long-term obstructive pulmonary disease is inhaled corticosteroids (ICS) and long acting beta-2 agonists. Study results on adverse effects of ICS on bone were conflicting. In the present study, we evaluated the effect of ICS on bone mineral density (BMD) of CWV(More)
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