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Early B-cell factors 2 and 3 (EBF2/3) regulate early migration of Cajal–Retzius cells from the cortical hem

• Francesca Gheri Chiara, Aurora Badaloni, +8 authors Sonja Rakić
• Developmental biology
• 2012

Cajal-Retzius (CR) cells play a crucial role in the formation of the cerebral cortex, yet the molecules that control their development are largely unknown. Here, we show that Ebf transcription… (More)

Complement Inhibition Promotes Endogenous Neurogenesis and Sustained Anti-Inflammatory Neuroprotection following Reperfused Stroke

• Andrew F Ducruet, Brad E. Zacharia, +9 authors E Sander Connolly
• PloS one
• 2012

BACKGROUND AND PURPOSE The restoration of blood-flow following cerebral ischemia incites a series of deleterious cascades that exacerbate neuronal injury. Pharmacologic inhibition of the C3a-receptor… (More)

Pharmacotherapy of cerebral ischemia.

• Andrew F Ducruet, Bartosz T. Grobelny, Brad E. Zacharia, Zachary L. Hickman, Mason L. Yeh, E Sander Connolly
• Expert opinion on pharmacotherapy
• 2009

BACKGROUND Ischemic stroke remains one of the leading causes of death and disability in the developed world. Despite many promising preclinical results, the only pharmacologic treatments proven… (More)

Robo1 modulates proliferation and neurogenesis in the developing neocortex.

• Mason L. Yeh, Yuko Gonda, +5 authors William D Andrews
• The Journal of neuroscience : the official…
• 2014

The elaborate cytoarchitecture of the mammalian neocortex requires the timely production of its constituent pyramidal neurons and interneurons and their disposition in appropriate layers. Numerous… (More)

Slit-roundabout signaling regulates the development of the cardiac systemic venous return and pericardium.

• Mathilda T. M. Mommersteeg, William D Andrews, +7 authors John G. Parnavelas
• Circulation research
• 2013

RATIONALE The Slit-Roundabout (Robo) signaling pathway has pleiotropic functions during Drosophila heart development. However, its role in mammalian heart development is largely unknown. OBJECTIVE… (More)

Disrupted Slit-Robo signalling results in membranous ventricular septum defects and bicuspid aortic valves

• Mathilda T. M. Mommersteeg, Mason L. Yeh, John G. Parnavelas, William D Andrews
• Cardiovascular research
• 2015

AIMS The mesenchymal cushions lining the early embryonic heart undergo complex remodelling to form the membranous ventricular septum as well as the atrioventricular and semilunar valves in later… (More)

The Neuroprotective Effect of Genetic Mannose-Binding Lectin Deficiency Is Not Sustained in the Subacute Phase of Stroke

• Andrew F Ducruet, Sergey A. Sosunov, +6 authors E Sander Connolly
• Translational Stroke Research
• 2011

The complement cascade is a critical mediator of the inflammatory response following cerebral ischemia. Recent work has demonstrated that genetic deficiency of mannose-binding lectin (MBL)… (More)

Isoflurane preconditioning affords functional neuroprotection in a murine model of intracerebral hemorrhage.

• Paul R. Gigante, Geoffrey Appelboom, +7 authors E Sander Connolly
• Acta neurochirurgica. Supplement
• 2011

INTRODUCTION Exposure to isoflurane gas prior to neurological injury, known as anesthetic preconditioning, has been shown to provide neuroprotective benefits in animal models of ischemic stroke.… (More)

Nerve growth factor in the hippocamposeptal system: evidence for activity-dependent anterograde delivery and modulation of synaptic activity.

• Lan Qing Guo, Mason L. Yeh, Verginia C Cuzon Carlson, Erin M. Johnson-Venkatesh, Hermes H. Yeh
• The Journal of neuroscience : the official…
• 2012

Neurotrophins have been implicated in regulating neuronal differentiation, promoting neuronal survival, and modulating synaptic efficacy and plasticity. The prevailing view is that, depending on the… (More)

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