Masayuki Kumagai

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BACKGROUND The efficacy of disulfiram in preventing an alcoholic relapse has been controversial. The aim of our study was to assess the efficacy of supervised disulfiram for the treatment of alcohol dependence with a multi-institutional study in Japan. METHODS In a single-blinded, randomized placebo-controlled study, we recruited 109 patients diagnosed(More)
The nesting behavior of a fluvial sculpin Cottus nozawae population was investigated in a stream–reservoir system on the Sainai River, northern Honshu Island, Japan in 2003, 2004 and 2006. Except for the usual rock nest-spawning type (RSN), two new types of spawning nest were found: hole nest spawning (HNS) and crevice nest spawning (CNS). The HNS type was(More)
A behavioral study was performed in an attempt to understand the role of central β-adrenoceptors in yawning in rats. Yawning was evoked by apomorphine and piribedil, mixed dopamine D1/D2-receptor agonists, but not by SK&F 38393 [1-phenyl-2,3,4,5-tetrahydro-(1H)-3-benzazepine-7,8diol], a dopamine Dr-receptor angonist. The apomorphine-induced yawning was(More)
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