Masayuki Ikenishi

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OBJECTIVE Recent reports have shbown an increase in serum phenytoin levels resulting in phenytoin toxicity after initiation of luoropyrimidine chemotherapy. To prevent phenytoin intoxication, phenytoin dosage must be adjusted. We sought to develop a pharmacokinetic model of the interaction between phenytoin and capecitabine. METHODS We developed the(More)
Noise in optical disk readout has been examined for different polarizations of the incident beam. The disks studied are bare grooved glass substrates, having different groove shapes or differing jaggedness in the sidewalls. We perform measurements for the electric field of the incident laser beam parallel to the track and perpendicular to the track using(More)
We used the prothrombin time international normalized ratio(PT-INR)to investigate the change in degree and term of warfarin following co-administration and after discontinuation of capecitabine. In this study, approximately 3 years of medical records of 7 patients receiving co-administration therapy of warfarin and capecitabine were obtained from 4(More)
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