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  • Hiroyuki Kakinuma, Takahiro Oi, +15 authors Koji Yamamoto
  • Chemistry, Medicine
  • Journal of medicinal chemistry
  • 2010 (First Publication: 22 April 2010)
  • Derivatives of a novel scaffold, C-phenyl 1-thio-D-glucitol, were prepared and evaluated for sodium-dependent glucose cotransporter (SGLT) 2 and SGLT1 inhibition activities. Optimization ofContinue Reading
  • Hirotaka Imai, Daigo Sumi, Akiharu Hanamoto, Masayuki Arai, Akira Sugiyama
  • Medicine, Biology
  • Journal of biochemistry
  • 1995 (First Publication: 1 October 1995)
  • A full-length cDNA clone for phospholipid hydroperoxide glutathione peroxidase (PHGPx) was isolated from a rat brain. The cDNA was 0.761 kb in length and encoded 170 amino acids, which included aContinue Reading
  • E Sawa, Masahide Takahashi, +6 authors Tsuyoshi Nishitoba
  • Chemistry, Medicine
  • Journal of medicinal chemistry
  • 1999 (First Publication: 1 August 1999)
  • We report the structural requirements of the C-terminal tripeptide derivative of Fas (Ac-Ser-Leu-Val-OH, 1) for the inhibitory activity of Fas/FAP-1 binding. The presence of a carboxyl group and aContinue Reading