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Evaluation of Transplanted Autologous Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium in Exudative Age-Related Macular Degeneration.
PURPOSE To report the results after 4 years of follow-up in a previously presented first case of induced pluripotent stem cell (iPSC)-derived retinal pigment epithelium (RPE) sheet autologousExpand
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Design of a Tumorigenicity Test for Induced Pluripotent Stem Cell (iPSC)-Derived Cell Products
Human Pluripotent Stem Cell (PSC)-derived cell therapy holds enormous promise because of the cells’ “unlimited” proliferative capacity and the potential to differentiate into any type of cell.Expand
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Gene and Induced Pluripotent Stem Cell Therapy for Retinal Diseases.
Given the importance of visual information to many daily activities, retinal degenerative diseases-which include both inherited conditions (such as retinitis pigmentosa) and acquired conditions (suchExpand
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A discrete neuronal circuit induces a hibernation-like state in rodents
Hibernating mammals actively lower their body temperature to reduce energy expenditure when facing food scarcity 1 . This ability to induce a hypometabolic state has evoked great interest owing toExpand
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A simple and static preservation system for shipping retinal pigment epithelium cell sheets
The ability to move cells and tissues from bench to bedside is an essential aspect of regenerative medicine. In this study, we propose a simple and static shipping system to deliver tissue‐engineeredExpand
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10 Questions: Clinical Outlook for iPSCs.
In an interview, we recently asked four leaders in the field to share their insights with us on the clinical outlook for hiPSCs. We present highlights from their responses here.
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