Masayo Fujimoto

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This study found that the use of a computer conferencing system in an R&D lab was significantly shaped by a set of intervening actors—mediators—who actively guided and manipulated the technology and its use over time. These mediators adapted the technology to its initial context and shaped user interaction with it; over time, they continued(More)
Epigenetic alterations in cancer, especially DNA methylation and histone modification, exert a significant effect on the deregulated expression of cancer-related genes and lay an epigenetic pathway to carcinogenesis and tumor progression. Global hypomethylation and local hypermethylation of CpG islands in the promoter region, which result in silencing tumor(More)
This study found that the use of a computer conferencing system in an R&D lab was significantly shaped by a set of intervening actors-mediators-who actively guided and manipulated the technology and its use over time. These mediators adapted the technology to its initial context and shaped user interaction with it; over time, they continued to modify the(More)
Increasing usage of ICT in medical organizations raises the issue of information security. This research study focuses on, and analyzes technology and management aspects for, information security of networked medical organizations through a teleradiology case study. A 'workshop' to gauge risk assessment was also established in which stakeholders, such as(More)
This paper reports on a study into the administrative activities surrounding a computer conferencing system used by a product development group within a large Japanese manufacturing firm. Drawing on interview and textual data, the study investigated the goals, deliberations, responsibilities, and outcomes of administrators of the group's conferencing(More)
  • Kazuo Okamura, Wanda Orlikowski, Masayo Fujimoto, Joanne Yates, Kazuo Okanura, Wanda J Orlikowski
We suggest that a mechanism for facilitating the context-specificity of technologies in use already exists in organizations, but is under-appreciated, under-utilized, and under-managed. We studied the use of a conferencing technology and found that its effectiveness was significantly shaped by a set of actors-technology mediators-who actively guided and(More)
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