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Pulmonary hypertension (PH), which is classified as group 5 in the clinical classification of PH, is sometimes a complication of Pulmonary langerhans cell histiocytosis (PLCH), and is associated with high mortality. A 36-year-old woman had suffered from severe dyspnea 9 years previously and was diagnosed with PLCH and was on a waiting list for a lung(More)
BACKGROUND A difference in systolic blood pressure (SBP) ≥10 mmHg between the arms is associated with an increased risk of coronary artery disease (CAD) and mortality in high-risk patients. METHODS AND RESULTS Four hundred and fourteen patients were divided into three groups according to the percent most severe luminal narrowing of a coronary artery as(More)
Smoking promotes arteriosclerosis and is one of the most important coronary risk factors. However, few studies have investigated the association between smoking habits and the severity of coronary stenosis as assessed by coronary computed tomography angiography (CTA). We enrolled 416 patients [165/251 = smoker (past and current)/non-smoker)]. They had all(More)
Many patients still have high blood pressure (BP) after treatment with angiotensin II type 1 (AT1) receptor blockers (ARBs). We compared the efficacy and safety of azilsartan to those of olmesartan in a prospective randomized clinical trial. Sixty-four hypertensive patients who were treated with ARBs other than azilsartan and olmesartan were enrolled in(More)
BACKGROUND Smoking is an important cardiovascular risk. We hypothesized that a ban on smoking in a hospital could decrease the in-hospital onset of acute myocardial infarction (AMI). METHODS Our hospital provided separate facilities for smokers and nonsmokers from 1981 to 2002. From 2002 to 2006, we began to introduce smoke-free zones throughout the(More)
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