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Web content is under the control of site owners, and therefore the site owners have the responsibility to make their content accessible. This is a basic assumption of Web accessibility. Users who want access to inaccessible content must ask the site owners for help. However, the process is slow and too often the need is mooted before the content becomes(More)
Engrailed is a key transcriptional regulator in the nervous system and in the maintenance of developmental boundaries in Drosophila, and its vertebrate homologs regulate brain and limb development. Here, we show that the functions of both of the Hox cofactors Extradenticle and Homothorax play essential roles in repression by Engrailed. Mutations that remove(More)
Caspase activation has been extensively studied in the context of apoptosis. However, caspases also control other cellular functions, although the mechanisms regulating caspases in nonapoptotic contexts remain obscure. Drosophila IAP1 (DIAP1) is an endogenous caspase inhibitor that is crucial for regulating cell death during development. Here we describe(More)
Inhibitors of apoptosis proteins (IAPs) interact with caspases and inhibit their protease activity, whereas the IAP-inhibitory proteins Smac/DIABLO in mammals and Reaper, Hid, and Grim in flies relieve IAP-mediated inhibition to induce cell death. Here we describe the functional characterization of the novel Drosophila cell death protein Sickle (Skl), which(More)
We propose the "ninja cursor" to improve the performance of target acquisition, particularly on large screens. This technique uses multiple distributed cursors to reduce the average distance to targets. Each cursor moves synchronously following mouse movement. We present the design and implementation of the proposed technique, including a method to resolve(More)
Collaborative accessibility improvement has great potential to make the Web more adaptive in a timely manner by inviting users into the improvement process. The Social Accessibility Project is an experimental service for a new needs-driven improvement model based on collaborative metadata authoring technologies. In 10 months, about 18,000 pieces of metadata(More)
Smartphones with touchscreen-based interfaces are increasingly used by non-technical groups including the elderly. However, application developers have little understanding of how senior users interact with their products and of how to design senior-friendly interfaces. As an initial study to assess standard mobile touchscreen interfaces for the elderly, we(More)
Cascading menus are commonly seen in most GUI systems. However, people sometimes choose the wrong items by mistake, or become frustrated when submenus pop up unnecessarily. This paper proposes two methods for improving the usability of cascading menus. The first uses the direction of cursor movement to change the menu behavior: horizontal motion(More)
We present the boomerang technique, which makes it possible to suspend and resume drag-and-drop operations. A throwing gesture while dragging an object suspends the operation, anytime and anywhere. A drag-and-drop interaction, enhanced with our technique, allows users to switch windows, invoke commands, and even drag other objects during a drag-and-drop(More)