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BACKGROUND Whether hepatic resection is indicated for elderly patients with hepatocellular carcinoma (HCC) remains controversial. METHODS This retrospective study evaluated surgical outcomes and prognostic factors in elderly patients with HCC who underwent hepatectomy. Overall survival rates and disease-free survival rates after hepatectomy were compared(More)
OBJECTIVE To investigate the role of Nrf2 in the pathogenesis of hepatic ischemia-reperfusion (I/R) injury. BACKGROUND Hepatic I/R injury is a serious complication that leads to liver failure after liver surgery. NF-E2-related factor 2 (Nrf2) is a transcription factor that plays a critical role in protecting cells against oxidative stress. Therefore, it(More)
BACKGROUND Sarcomatous intrahepatic cholangiocarcinoma (ICC) is a rare histological variant of ICC. The prognosis of sarcomatous ICC is poorly understood. METHODS We analyzed the prognosis of sarcomatous ICC by reviewing the previous reports and our own case. RESULTS Only 15 cases of sarcomatous ICC have been reported in the English-language literature(More)
This 10-b 50-MSamples/s SAR analog-to-digital converter (ADC) features on-chip digital calibration techniques, comparator offset cancellation, a capacitor digital-to-analog converter (CDAC) linearity calibration, and internal clock control to compensate for PVT variations. A split-CDAC reduces the exponential increase in the number of unit capacitors needed(More)
We have developed hybrid amphiphilic polymers consisting of a silicone backbone modified with hydrocarbon chains and hydrolyzed silk peptides. These polymers are molecularly soluble neither in water nor in most of organic solvent, but are attractive with these solvents. We assume that this property enables the polymers to form "an independent third phase"(More)
Toxins in shellfish, which are responsible for paralytic poisonings, undergo reductive transformation when incubated with the homogenate of various portions of the scallop, Placopecten magellanicus. The transformation includes the reductive elimination of O-sulfate groups, a change that is most evident in the locomotor tissue homogenates. The commercially(More)
A split capacitor DAC calibration method is proposed that a bridge capacitor larger than conventional design allows a tunable capacitor to compensate for mismatch. To guarantee proper calibration, a comparator with digital timing control offset cancellation is proposed. An 8-bit successive approximation ADC with 4b+4b split capacitor DAC calibration has(More)
INTRODUCTION We introduce a technique for pancreaticojejunostomy with closure of the pancreatic stump by endoscopic linear stapler as a reliable intervention with benefits for pancreatic resection in laparoscopic pancreaticoduodenectomy (Lap-PD). MATERIALS AND SURGICAL TECHNIQUE Following laparoscopic resection, we perform pancreaticojejunostomy under(More)
BACKGROUND/AIM To preserve pancreatic function, segmental pancreatectomy has been proposed for benign or low-malignancy tumors in the pancreatic body. Indications for the procedure, however, are still controversial. METHODS In this study, we investigated the advantages and disadvantages of segmental pancreatectomy compared with distal pancreatectomy and(More)