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Intervertebral disc regeneration using platelet-rich plasma and biodegradable gelatin hydrogel microspheres.

• Masateru Nagae, Takumi Ikeda, +7 authors Toshikazu Kubo
• Tissue engineering
• 2007

This study evaluated the regenerative effects of platelet-rich plasma (PRP) for the degenerated intervertebral disc (IVD) in vivo. After induction of IVD degeneration in rabbits, we prepared PRP by… (More)

Platelet-rich plasma enhances the initial mobilization of circulation-derived cells for tendon healing.

• Yoshiteru Kajikawa, Toru Morihara, +7 authors Toshikazu Kubo
• Journal of cellular physiology
• 2008

Circulation-derived cells play a crucial role in the healing processes of tissue. In early phases of tendon healing processes, circulation-derived cells temporarily exist in the wounded area to… (More)

Characterization of in vivo effects of platelet-rich plasma and biodegradable gelatin hydrogel microspheres on degenerated intervertebral discs.

• Kazuhide Sawamura, Takumi Ikeda, +10 authors Toshikazu Kubo
• Tissue engineering. Part A
• 2009

We have previously shown that administration of platelet-rich plasma-impregnated gelatin hydrogel microspheres (PRP-GHMs) into a degenerated intervertebral disc (IVD) markedly suppresses progression… (More)

Effects of stress-shielding on the dynamic viscoelasticity and ordering of the collagen fibers in rabbit Achilles tendon.

• Kazuya Ikoma, Masamitsu Kido, +7 authors Toshikazu Kubo
• Journal of orthopaedic research : official…
• 2013

We investigated the effects of stress-shielding on both viscoelastic properties and microstructure of collagen fibers in the Achilles tendon by proton double-quantum filtered ((1) H-DQF) NMR… (More)

Positive effect on bone fusion by the combination of platelet-rich plasma and a gelatin β-tricalcium phosphate sponge: a study using a posterolateral fusion model of lumbar vertebrae in rats.

• Shin-ichi Okamoto, Takumi Ikeda, +7 authors Toshikazu Kubo
• Tissue engineering. Part A
• 2012

We developed a novel method for bone fusion by combining platelet-rich plasma (PRP) and a gelatin β-tricalcium phosphate (β-TCP) sponge. The PRP is an autologous concentration of platelets that… (More)

Tubular surgery with the assistance of endoscopic surgery via midline approach for lumbar spinal canal stenosis: a technical note

• Yasuo Mikami, Masateru Nagae, Takumi Ikeda, Hitoshi Tonomura, Hiroyoshi Fujiwara, Toshikazu Kubo
• European Spine Journal
• 2013

We devised a tubular surgery with the assistance of endoscopic surgery via midline approach to the spinal canal to preserve the bilateral facet joints and the paravertebral muscles when treating… (More)

Urban versus rural differences in the occurrence of hip fractures in Japan’s Kyoto prefecture during 2008–2010: a comparison of femoral neck and trochanteric fractures

• Motoyuki Horii, Hiroyoshi Fujiwara, +7 authors Toshikazu Kubo
• BMC musculoskeletal disorders
• 2013

BACKGROUND To investigate the differences in the characteristics of femoral neck and trochanteric fractures between urban and rural areas of Kyoto Prefecture in Japan. METHODS Fracture type (neck… (More)

Hepatocyte growth factor/c-met promotes proliferation, suppresses apoptosis, and improves matrix metabolism in rabbit nucleus pulposus cells in vitro.

• Hidenobu Ishibashi, Hitoshi Tonomura, +7 authors Toshikazu Kubo
• Journal of orthopaedic research : official…
• 2016

The etiology of intervertebral disc (IVD) degeneration is closely related to apoptosis and extracellular matrix degradation in nucleus pulposus (NP) cells. These defects in NP cells are induced by… (More)

Comparison with Magnetic Resonance Three-Dimensional Sequence for Lumbar Nerve Root with Intervertebral Foramen

• Hiroyuki Takashima, Tsuneo Takebayashi, +8 authors Toshihiko Yamashita
• Asian spine journal
• 2016

STUDY DESIGN Prospective study based on magnetic resonance (MR) imaging of the lumbar spinal root of the intervertebral foramen. PURPOSE This study was to compare MR three-dimensional (3D)… (More)

Successful endoscopic submucosal dissection of duodenal cancer.

• Shuhei Yoshida, Masaaki Shimada, +7 authors Masahiro Yoshino
• Endoscopy
• 2008

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