Masatake Kuroha

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An association between FCGR3A-158 V/F polymorphism and biological responses to infliximab has been reported in Crohn’s disease (CD) in Western countries. However, little is known about the mechanism by which gene polymorphism affects the responses to infliximab. The aims of this study were to confirm the association in Japanese CD patients and to reveal the(More)
OBJECTIVE Stress is thought to be one of the triggers of relapses in patients with inflammatory bowel disease (IBD). We examined the rate of relapse in IBD patients before and after the Great East Japan Earthquake. DESIGN A retrospective cohort study. SETTINGS 13 hospitals in Japan. PARTICIPANTS 546 ulcerative colitis (UC) and 357 Crohn's disease (CD)(More)
The upper gastrointestinal tract is not generally considered a target organ in ulcerative colitis (UC). However, several cases showing upper gastrointestinal involvement in UC have been reported. In this report, we present 2 rare cases of diffuse duodenitis accompanying pancolonic UC. Case patient 1 was a 44-year-old man who developed diffuse duodenitis(More)
Background/Aims. Antitumor necrosis factor antibodies and calcineurin inhibitors have shown good therapeutic efficacy for steroid-refractory ulcerative colitis (UC). Although some studies have compared the efficacy of infliximab (IFX) and cyclosporin A, there are no published studies comparing IFX and tacrolimus (Tac). This study aimed to compare(More)
In response to an enquiry regarding a possible discrepancy in our original Table 2 data, we-the authors of the paper-recalculated the material. We were able to confirm that our original calculation of the raw data-which had excluded certain missing values-was appropriate, but in recalculating we found minor errors in the Table 2 values. We have corrected(More)
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