Masashi Oguri

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The stratum corneum (SC) plays a fundamental role in the barrier function of the skin. The SC consists of corneocytes embedded in a lipid matrix. The main lipid classes in the lipid matrix are ceramides (CERs), cholesterol (CHOL) and free fatty acids (FFAs). The aim of this study was to examine the effect of the chain length of FFAs on the thermotropic(More)
The lipid matrix in the stratum corneum (SC) plays an important role in the barrier function of the skin. The main lipid classes in this lipid matrix are ceramides (CERs), cholesterol (CHOL) and free fatty acids (FFAs). The aim of this study was to determine whether a variation in CER subclass composition and chain length distribution of FFAs affect the(More)
The effects of the removal of 18-MEA on the dynamic contact angle (advancing contact angle and receding contact angle) and friction force (friction force microscopy (FFM)) were examined in the present study. Chemically untreated hair tresses formed more finely ordered bundles, with the fibers aligned more parallel to each other, in the wet state, and lying(More)
The effect of the anteiso-branch moiety of 18-MEA (18-methyleicosanic acid) to create a persistent hydrophobicity of alkaline-color-treated weathered hair treated with 18-MEA/SPDA (stearoxypropyldimethylamine) was investigated by comparing a straight-chain fatty acid (n-heneicosanoic acid, n-HEA) and an iso-branch fatty acid (19-methyleicosanic acid,(More)
The effects of Sox21 gene deletion on hair lipids have been studied. For the cuticle-specific bound lipid 18-methyl eicosanoic acid (18-MEA), which was found to predominantly exist as the free form in Sox21(-/-) hair, total levels and distribution were unexpectedly unchanged. This indicates that while the biosynthesis of 18-MEA is unaffected, its covalent(More)
A technology for the deposition of a persistent hydrophobicity to alkaline-color-treated weathered hair surfaces using 18-MEA (18-methyleicosanoic acid) is presented. Two approaches were examined in order to make 18-MEA bind tightly to the alkaline-color-treated weathered hair surface. One was to apply 18-MEA as an acid form and the other was to apply(More)
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