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Toshiba submitted six runs in the NTCIR crosslingual task. Our basic approach was translation of Japanese search requests into English using a commercial machine translation system. Runs TSB1, TSB5 and TSB6 used the AS-TRANSAC machine translation system, while, for comparison , TSB3 used queries manually constructed by a bilingual. TSB2 is TSB1 plus local(More)
Pulmonary macrophages are one of the sources of various antioxidant and detoxification enzymes for which NF-E2-related factor 2 (Nrf2) is a key transcriptional factor. Although Nrf2 deficiency reportedly induces severe emphysema in mice exposed to cigarette smoke (CS), no reports have studied Nrf2 regulation in chronic obstructive pulmonary disease (COPD).(More)
BACKGROUND We encountered eight early amnestic mild cognitive impairment (aMCI) patients (early MCI group) who did not fulfill the diagnostic criteria for aMCI. We compared the scores of neuropsychological examinations as well as the cerebral metabolic rate for glucose consumption (CMRglc) decrease on (18)F-FDG PET examination between the early MCI group(More)
Toshiba participated in the Japanese monolingual track and the English-Japanese cross-language track at NTCIR-3, and achieved the highest retrieval performances among the DESCRIPTION runs. Our pre-submission experiments using the KIDS system fo-cused primarily on effective Japanese monolingual retrieval, and addressed several problems including term(More)
This paper describes two new features of the BRIDJE system for cross-language information access. The first feature is the partial disambiguation function of the Bi-directional Retriever, which can be used for search request translation in cross-language IR. Its advantage over a " black-box " machine translation approach is consistent across five test(More)
We developed a knowledge and information on demand system, KIDS, which structures free-form text as knowledge to provide the user with knowledge fit for his natural language query. For a period of four years, we carried out knowledge sharing experiments using the system at a research center that includes around 1,000 researchers engaged in various fields(More)
Coenzyme Q10 (CoQ10) is essential for ATP production in the mitochondria, and is an important antioxidant in every biomembrane and lipoprotein. Due to its hydrophobicity, a binding and transfer protein for CoQ10 is plausible, but none have yet been isolated and characterized. Here we purified a CoQ10-binding protein from human urine and identified it to be(More)
INTRODUCTION Asthma is a chronic inflammatory disorder of the airways, involving oxidative stress. Upon oxidative stress, glutathione covalently binds to protein thiols to protect them against irreversible oxidation. This posttranslational modification, known as protein S-glutathionylation, can be reversed by glutaredoxin 1 (Glrx1) under physiological(More)
BACKGROUND The aim of the study was to examine the longitudinal change in quality of life components of patients with chronic obstructive pulmonary disease (COPD). METHODS In the Hokkaido COPD Cohort Study, 261 subjects were appropriately treated and followed over 5 years with a 74% follow-up rate at the end. The longitudinal changes in St George's(More)
INTRODUCTION Anaplastic transformation of well-differentiated papillary thyroid carcinoma at distant metastasis sites is rare. To the best of our knowledge, this is the first report of an autopsy case of anaplastic transformation of papillary thyroid carcinoma in multiple lung metastases presenting with a malignant pleural effusion. CASE PRESENTATION We(More)