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Synthetic and naturally occurring antioxidants have a wide variety of biological actions in rodents in addition to their primary antioxidant activity. Some of the included biological effects are of… (More)
The efficacies of N-acetylcysteine (NAC), phenylethyl isothiocyanate (PEITC), and 1-O-hexyl-2,3,5-trimethylhydroquinone (HTHQ) at preventing the neurotoxicity and testicular toxicity of acrylamide… (More)
Thyroid cell proliferation caused by environmental compounds is well known to be associated promotion of carcinogenesis. For example, kojic acid, a secondary fungal metabolite, induces cell… (More)
Tocotrienol is an antioxidant which has found commercial application as a food additive and health supplement all over the world. Since there have been no reports regarding toxicological effects of… (More)
Flumequine (FL), a quinolone-antibiotic used for veterinary treatment of infections, was found to elicit hepatocellular tumors in a conventional 18-month carcinogenicity study in mice, and… (More)
To elucidate target molecules of white matter development responding to hypothyroidism, global gene expression profiling of cerebral white matter from male rat offspring was performed after maternal… (More)